Charles E. Binkley, MD, FACS

Surgeon • Bioethicist • AI Expert

About Dr. Binkley

As a surgeon, bioethicist, and academic health system leader, Dr. Charles E. Binkley drives strategic initiatives to responsibly integrate AI into care delivery systems, enhance clinical decision-making, improve patient outcomes, and deliver measurable impact. He is chair of the AI Task Force at Hackensack Meridian School of Medicine (HMSOM), where he leads academic policy implementation, curricular integration, faculty development, and research involving AI.

He brings a rare combination of clinical, ethical, and practical operational expertise, combined with dynamic relational leadership, to the evaluation, integration, and governance of AI. His work bridges practice and theory, and he advises on local and national AI implementation strategies. His scholarship, including the book Encoding Bioethics: AI in Clinical Decision Making, describes how AI can support trustworthy, clinically grounded, and strategically sustainable AI in health systems.

Selected Publications

Books

  • Encoding Bioethics: AI in Clinical Decision-Making

    Binkley CE, Loftus TJ. The University of California Press, June 2024

Peer-Reviewed Articles

  • Ethical Rationing of Personal Protective Equipment to Minimize Moral Residue During the COVID-19 Pandemic.

    Binkley CE, Kemp DS. J Am Coll Surg. 2020;230(6):1111-1113. PMID: 32278727

  • Ethical Centralization of High-risk Surgery Requires Racial and Economic Justice.

    Binkley CE, Kemp DS. Ann Surg. 2020;272(6):917-918. PMID: 32956174

  • Does Intraoperative Artificial Intelligence Decision Support Pose Ethical Issues?

    Binkley CE, Green BP. JAMA Surg. Published online June 16, 2021. PMID: 34132749

  • Who, If Not the FDA, Should Regulate Implantable Brain-Computer Interface Devices?

    Binkley CE, Politz MS, Green BP. AMA J Ethics. 2021;23(9):E745-E749. Published 2021 Sep 1. PMID: 34710035

  • How Should Surgeons Communicate About Palliative and Curative Intentions, Purposes, and Outcomes?

    Binkley CE. AMA J Ethics. 2021;23(10):E794-E799. Published 2021 Oct 1. PMID: 34859773

  • The Complex Relationship between Disability Discrimination and Frailty Scores.

    Reynolds JM, Binkley CE, Shuman A. Am J Bioeth. 2021;21(11):74-76. PMID: 34710022

  • Disproof of Concept: Resolving Ethical Dilemmas Using Algorithms.

    Pilkington B, Binkley C. Am J Bioeth. 2022;22(7):81-83. PMID: 35737493

  • Assessing Trustworthy AI in Times of COVID-19: Deep Learning for Predicting a Multiregional Score Conveying the Degree of Lung Compromise in COVID-19 Patients.

    Allahabadi H, Amann J, Balot I, et al. IEEE Trans Technol Soc. 2022;3(4):272-289. Published 2022 Jul 29. PMID: 36573115

  • Should We Rely on AI to Help Avoid Bias in Patient Selection for Major Surgery?

    Binkley CE, Kemp DS, Braud Scully B. AMA J Ethics. 2022;24(8):E773-E780. Published 2022 Aug 1. PMID: 35976935

  • From the Eyeball Test to the Algorithm - Quality of Life, Disability Status, and Clinical Decision Making in Surgery.

    Binkley CE, Reynolds JM, Shuman A. N Engl J Med. 2022;387(14):1325-1328. PMID: 36198184

  • The Actionless Agent: An Account of Human-CAI Relationships.

    Binkley CE, Pilkington B. Am J Bioeth. 2023;23(5):25-27. PMID: 37130395

  • Informed Consent for Clinician-AI Collaboration and Patient Data Sharing: Substantive, Illusory, or Both.

    Binkley CE, Pilkington BC. Am J Bioeth. 2023;23(10):83-85. PMID: 37812116

  • Respecting the Value-Laden Nature of Participant Preferences: AI, Digital Phenotyping, and Psychiatry.

    Pilkington B, Noto J, Silverstein D, Binkley CE. Am J Bioeth. 2024;24(2):93-96. PMID: 38295243

  • A Holistic, Multi-Level, and Integrative Ethical Approach to Developing Machine Learning-Driven Decision Aids.

    Ho A, Brake J, Palmer A, Binkley CE. Am J Bioeth. 2024;24(9):110-113. PMID: 39226003

  • Discerning the Nature of MAMLS: Research, Quality Improvement, or Both?

    Binkley C, Meda R, de Lara J. Am J Bioeth. 2024;24(10):98-100. PMID: 39283383

  • Health AI poses distinct harms and potential benefits for disabled people.

    Binkley CE, Reynolds JM, Shuman AG. Nat Med. 2025;31(1):12-13. PMID: 39810004

  • Clarifying When Consent Might Be Illusory in Notice and Explanation Rights.

    Pilkington B, Binkley CE. Am J Bioeth. 2025;25(3):126-128. PMID: 39992845

  • Predicting the Future: Informational Agency and the Right to Notice and Explanation in the Use of Personal Information.

    Binkley CE, Ho A, Palmer A. Am J Bioeth. 2025;25(3):135-138. PMID: 39992838

  • Governance of Direct-to-User Digital Mental Health Tools: Emphasizing Transparency over Paternalism.

    Panda OD, Binkley CE. Hastings Cent Rep. 2025;55(3):29-33. PMID: 40557920

  • An early pipeline framework for assessing vendor AI solutions to support return on investment.

    Binkley CE, Bouslov D, Zaidi A, et al. NPJ Digit Med. 2025;8(1):368. Published 2025 Jun 17. PMID: 40523928

  • A Matter of Trust: Recovering Lost Principles to Ethically Assess AI in Health Care.

    Pilkington B, Binkley CE, Green BP. Journal of Philosophy and Medicine. Accepted, January 2024 (in press)

Curriculum Vitae

Download CV (PDF)